“ZERO-MOZ” for Long-Term Inhibition of Breeding of “Mosquitoes” that Cause Infectious Diseases such as Malaria and DengueZERO MOZ JAPAN Co.,Ltd


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“ZERO-MOZ” is the product name and origin of the company name, and means “Make Mosquitoes Zero”

Points to be noted

  • Control infectious diseases by inhibiting the breeding of mosquitoes
  • Contribute to the creation of a stable society around the world by reducing infectious diseases without environmental impact
  • Gain knowledge on infectious diseases through academia-industrial collaboration with Nagasaki University

At present, solving the problem of malaria, which is one of the 3 major infectious diseases in the world, on a global scale is an important issue. A fact that cannot be overlooked is that nearly 500 million people are infected with malaria every year with more than 1 million people dying from the disease. More than 90% of the infections occur in Sub-Saharan Africa, even among them, the mortality rate of young children under the age of 5 is high, and one person is said to die every 30 seconds.

Map showing the occurrence of malaria

“Mosquitoes” are the mediators of infectious diseases such as malaria and dengue fever in humans. “ZERO-MOZ” is a formulation developed to inhibit the breeding of “Mosquitoes”, which can be said to be a worldwide problem, for a long period without environmental impact.

ZERO-MOZ exhibits its effectiveness when mosquitoes are in the larval stage (maggot). ZERO-MOZ disrupts the balance of hormones from the egg stage inhibiting the development into an adult, and prevents the growth of 99.95% of mosquitoes. Other advantages of ZERO-MOZ are (1) High safety, (2) Low cost, (3) Easy to use (just put into the source of mosquitoes such as puddles), and (4) Can control for long periods (6 months) with stability.
Instead of mosquito eradication, ZERO-MOZ stops the growth of the maggots before they turn into adults, and novelty of the product is that it works from a perspective that is completely different from current methods such as spraying of insecticides. If the mosquito larva remains a maggot, it becomes fish feed, and two problems can be solved together without harming the ecosystem.

Sites where ZERO-MOZ is used. Used in waterways where mosquitoes tend to breed

We spoke with Mr. Iwashita Tomoaki, managing director of Zero Moz Japan Co., Ltd on the development of ZERO-MOZ.
He said, “We were originally a water purification company engaged in research. During our overseas business trips, we went into the jungles many times, and there were requests from local people to develop a formulation for inhibiting ‘Mosquitoes’, which cause infectious diseases.
Even in Japan, Malaria has a long history, occurring in the Yaeyama Islands of Okinawa and Amakusa in Kumamoto from ancient times. A few years ago, there was news of dengue from Yoyogi Park in Tokyo. Though mosquitoes caused both the above incidents, the sufferings due to infectious diseases is low compared to some countries in Africa. In developing countries, many domestic conflicts take place because the residents are not able to lead a stable life, and one of the causes is also said to be the spread of infectious diseases such as malaria.
If a formulation to inhibit ‘Mosquitoes’ is developed, mortality rate of infants who die due to infectious diseases will also reduce. This will allow people of developing countries to live peacefully. Supported by such a social mission, we decided to launch ZERO-MOZ Japan in addition to our water purification company in 2010”.

The product was developed utilizing the experience of Mr. Iwashita from his previous company and the business was expanded with the main goal of spreading ZERO-MOZ to the developing countries. At present, ZERO-MOZ is sold in countries such as Bangladesh, Myanmar, and Malaysia in Asia, Chad and Angola in Africa, and Mexico and Honduras in Central and South America through local trading companies.

For the first time, local production is scheduled to start in Bangladesh. In the future, they plan to proceed with local production even in other countries. Manufacturing the product locally helps to create jobs in each country. Cost of production and price of raw materials can be reduced with local production enabling the product to be sold at a lower price, which increases opportunities for people to buy ZERO-MOZ in that country.

The company is advancing business development from Japan to the world and the demand for ZERO-MOZ is seeing a gradual increase in developing countries. Mr. Iwashita told us that the mission of ZERO-MOZ is to help people around the world so that they can live peacefully.

Interview Date: November 14, 2018


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